Spiroxatrine

Today we enter the fascinating world of Spiroxatrine, a topic that has captured the attention of millions of individuals around the world. From its origins to its impact today, Spiroxatrine has been the object of study, debate and admiration. With a legacy that spans centuries, Spiroxatrine has left an indelible mark on different aspects of society. In this article we will explore the history, importance and repercussions of Spiroxatrine, providing a deeper insight into a topic that continues to generate interest and inspiration today.
Spiroxatrine
Names
IUPAC name
8-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)-1-phenyl-1,3,8-triazaspirodecan-4-one
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
MeSH Spiroxatrine
UNII
  • InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26) checkY
    Key: JVGBTTIJPBFLTE-UHFFFAOYSA-N checkY
  • O=C2NCN(c1ccccc1)C23CCN(CC3)CC4Oc5ccccc5OC4
Properties
C22H25N3O3
Molar mass 379.460 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
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Spiroxatrine is a drug which acts as a selective antagonist at both the 5-HT1A receptor and the α2C adrenergic receptor. It is an analog of spiperone and also has some dopamine antagonist effects.

References

  1. ^ Terrón, J. A.; Ibarra, M; Ransanz, V; Hong, E; Villalón, C. M. (1993). "The alpha-antiadrenergic properties of spiroxatrine, a ligand of serotonergic 5-HT1A receptors". Archivos del Instituto de Cardiología de México. 63 (4): 289–95. PMID 8105762.